   
|
|
| |
INTRODUCTION
A total blood hemoglobin (Hb) measurement method is shown which does not disturb the subject's skin. Results were obtained using MinforMed's non-invasive blood analyzer prototype (patent pending). A light is shined onto a body part, through the skin, engaging the blood. The emerging light is analyzed for Hb's signature strength in the visible and near infrared region. Orthogonal decomposition methods are used to extract the Hb data from the complete spectrum. Results were compared to a laboratory-grade instrument that uses a drop of blood. A Hb range from 11 g/dL through 19 g/dL shows excellent correlation, r2=0.97. Other characteristics of the complete spectrum give indication of additional blood analytes, most notably bilirubin and water. Initial results are also shown indicating how light scattering varies with Hb concentration. Approximate residual skin and tissue spectrum is found by removing the spectral signature of the four Hb components (oxy-Hb, deoxy-Hb, carboxy-Hb and met Hb) from the complete spectrum. This procedure yields the least squares concentrations of the individual Hb components.
|
|
|
|
|
|
|